Pericytes regulate BBB permeability via transforming growth factor-, vascular endothelial growth factor, fibronectin, claudin-5, integrin 1, platelet-derived growth factors receptor-1, connexin-43, monocyte chemoattractant protein-1, CCAAT/enhancer binding protein homologous protein, and transcription factor 4
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If they make an exception for one patient, they may feel pressured to do so for others, leading to a system where ad-hoc changes become the norm
International Journal of Pharmaceutics, 587 , Article 119491
Insightful article